Functional Microbiome Therapies
Based on our research, we believe that the common denominator underlying each intestinal microbiome is a network of interconnected, interdependent and metabolic functions that are essential for the host and the microbiome.
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PharmaBiome has developed unique technologies to access the entire range of intestinal bacteria for the design and production of function-based consortia at scale.
Read about our differentiated technologies
We are a pre-clinical stage spinoff from the ETH Zurich, combining key expertise in microbiology, biotechnology and the molecular disease mechanisms that involve the microbiome.
See the expertise of our board, advisors and operational team
Our Vision
“We are the global leader in microbiome translation, advancing effective drug products through rigorous science.”
Why Microbiome Function Matters
Research informs our belief that the smallest relevant biological unit is the function, delivered by intestinal bacteria, and not the bacterial strain. These bacteria interact in a complex functional network to achieve a metabolically balanced microbiome.
Science of the Microbiome as a Network
The human microbiome fulfills a variety of functions. Each function is encoded in a set of bacteria that each have several functions under different circumstances. A bacterial consortium needs to be versatile, balanced and cover all the essential functions.
Our Approach
We take a bottom-up approach and engineer bacterial consortia based on their metabolic interactions. Our deep understanding of function drives the selection of individual strains to be assembled and co-cultured with our groundbreaking technology.
Therapies
Microbiome therapies go beyond FMT and are targeted to introduce a functionality. Starting with the biology of a specific disease, a tailored consortium of bacteria is mixed and co-cultured to reverse a dysbiosis.
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